ATAC-seq is a high-throughput sequencing method used to analyze genome-wide chromatin accessibility, which is crucial for understanding the global epigenetic regulation of gene expression. Chromatin accessibility refers to the extent to which nuclear macromolecules can interact with chromatinized DNA, enabling transcription and other biological processes. Consequently, ATAC-seq provides valuable insights into the genome’s regulatory landscape by identifying regions where DNA is accessible for binding by various cellular factors.
